Entomotoxicology, experimental set-up and interpretation for forensic toxicologists.

نویسندگان

  • Matthias Gosselin
  • Sarah M R Wille
  • Maria del Mar Ramírez Fernandez
  • V Di Fazio
  • Nele Samyn
  • Gert De Boeck
  • Benoit Bourel
چکیده

Forensic entomotoxicology studies the usefulness of insects as alternative toxicological samples. Use of insects as alternative matrix for drug detection is well documented and recommended when conventional matrices such as blood, urine or internal organs are no longer available. However, several limitations of entomotoxicology have been highlighted, especially concerning interpretation of the drug concentrations in insects on human forensic cases. In addition, the lack of knowledge in pharmacokinetic of drugs in insects, large variability of experimental set-up and toxicological analysis compromise the utility of this science. This review focuses on the current knowledge of factors influencing drug detection in insects. Reasons for the current limitations, but also recommendations for future research are discussed and proposed in this paper.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Estimating the measurement uncertainty in forensic blood alcohol analysis.

For many reasons, forensic toxicologists are being asked to determine and report their measurement uncertainty in blood alcohol analysis. While understood conceptually, the elements and computations involved in determining measurement uncertainty are generally foreign to most forensic toxicologists. Several established and well-documented methods are available to determine and report the uncert...

متن کامل

The Importance of Cooperation in Forensic Sciences: The Entomotoxicology

The continuous development of forensic sciences has given his contribution to the formation of different kind of highly skilled and specialized scientists who have to work together in order to help judicial authority and police to understand dynamics of a criminal event. These are experts in different fields of traditional sciences, such as chemistry, biology, physics, entomology, but they also...

متن کامل

Interpretation of Ethanol Analysis in Postmortem Specimens

Since alcohol is a general central nervous system depressant, it affects the motor and cognitive performance. Alcohol abuse is a major cause of medical and social problems. Additionally, to determine cause of death in legal medicine centers, alcohol analysis is the most frequently performed test in forensic toxicology laboratories. Accurate interpretation of ethanol concentration at the time...

متن کامل

Drug concentrations in post-mortem femoral blood compared with therapeutic concentrations in plasma

Therapeutic drug concentrations measured in plasma are of limited value as reference intervals for interpretation in post-mortem (PM) toxicology. In this study, drug concentration distributions were studied in PM femoral venous blood from 57 903 Finnish autopsy cases representing all causes of death during an 11-year period. Cause-of-death information was obtained from death certificates issued...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Forensic science international

دوره 208 1-3  شماره 

صفحات  -

تاریخ انتشار 2011